Chemometrics and Chemoinformatics Research Group Mehdi Jalali Heravi Professor
	Department of Chemistry Sharif University of Technology
	Office: +98-21-66165315
	Lab:    +98-21-66165329			Sweet moments in our group...
	jalali@sharif.edu
	Adress: Chemistry Department, Sharif University of Technology, P.O. Box 11365-9516, Tehran, Iran
	Ph.D: Surrey University, UK (1978)
	M.Sc: Surrey University, UK (1975)
	B.Sc: Ferdowsi University, Iran (1973)
Research Interests			Research Group
Experimental Design			Present Members:
	The design of experiments is a discipline of Chemometrics that its purpose is to deliver as much information as possible with a minimum of experimental or financial effort. This information is then employed in the construction of sensible models of the objects under investigation. Optimization of solid-phase microextarction and  ultrasonic solvent extraction  are some experimental design studies which were investigated in our laboratory.			Right to left: R.S. Moazeni, H. Ebrahimi, M. Asadollahi, Prof. M. Jalali, H. Parastar, A. Mani see full size image
			Group members projects:		Former group members:
QSAR/QSPR			Ahmad Mani (PhD Student)		Dr. H. Saadi		Dr. S. Maesom
	Quantitative Structure Property/Activity Relationship is the process by which chemical structure is quantitatively correlated with a well defined process, such as chemical property/biological activity. We have been used linear and nonlinear techniques such as MLR, ANN, GA, K-PLS, ANFIS, CART and PSO for modeling of retention times and mobilities of various compounds and also biological activities of anti-HIV, anti-Alzheimer and anti-cancer drugs.
			Rudabeh Sadat Moazeni (PhD Student)		Dr. A. Kyani		Dr. P. Shahbazikhah
			Arafeh Bigdeli (PhD Student)		Dr. M. H. Fatemi		M.R.Pourhaghighi
					Dr. M. Asadollahi		F. Hakimi
					Dr. A. Hassanzadeh		S.Karimi
					B.Zekavat		H. Paeenmahale
					F. Darvizeh		Dr. Hadi Parastar
			Dr. Heshmat Ebrahimi M.Sc students:
							Mehdi Karimi
			Rezvan Torkashvand, Hossein Robat Jazi
			Books & books Chapter:
			1- Artificial neural networks: Methods and applications
Multivariate Curve Resolution			2- Chemometrics methods in capillary electrophoresis. Edited by Grady Hanrahan & Frank A. Gomez, Part III chapter 14, Publisher: John-Wiely & Sons (2010).
	Multivariate curve resolution techniques (MCR) can be used for the analysis of unresolved peaks. These techniques would resolve multi-component mixtures into a simple model consisting of a composition-weighted sum of signals of the pure components. Analysis of essential oils of Iranian plants, fish oils and study of denaturation mechanism of hemoglobin carried out in our laboratory using Chemometric resolution techniques.		3- General Chemistry for Engineering, M. Jalali-Heravi. G. A. Parasfar, M.R.Saidi and M. Ghiaci, Esfahan University of Technology Publ., Esfahan, Iran, Fourth Edition 2002
			Courses taught:
			Experimental design
			New topics in analytical chemistry
			Analytical spectroscopic methods
			Laser in chemistry
			Physical and chemical methods of separation
Proteomics			Molecular spectroscopy
	Proteomics  is the systematic and comprehensive identification and quantification of proteins expressed from cells, tissues or organisms in terms of quality, structural modification, location within cells, activity and function. Peptide mapping and modeling of peptide mobilities in different modes of capillary electrophoresis are examples of proteomics studies performed in our group.		Instrumental analysis
			Analytical chemistry I & II
			General chemistry
			Executive Positions:
			General director of assesment and promotion of SUT.
			Department Chair, Sharif University of Technology, 1998-2002.
			Research Vice-Chairman of Faculty of Science, University of Kerman, 1991-1992.
			Department Chair, University of Kerman, 1985-1987.
Designed by: M. Asadollahi	Go Top